| Club | Tee | Day | Date | Home Away/Result | Match Manager |
| Copthorne (A) | 8.30 | WEDNESDAY | 24/03/2021 | Cancelled | Nigel Cook |
| Haywards Heath (H) | 8.30 | WEDNESDAY | 14/04/2021 | Postponned | Ray Dennett |
| East Sussex National (A) | 8.40 | THURSDAY | 22/04/2021 | Cancelled | Graham Davey |
| Littlehampton (H) | 8.30 | MONDAY | 26/04/2021 | Cancelled | Gerry Greensmith |
| Hill Barn (A) | 8.30 | WEDNESDAY | 28/04/2021 | Cancelled | David Bunting |
| Cooden Beach (H) | 8.30 | MONDAY | 10/05/2021 | WON 6-2 | Dave Boys |
| Goodwood (A) | 8.30 | WEDNESDAY | 12/05/2021 | LOST 4-1 | David Bunting |
| Copthorne (H) | 8.30 | MONDAY | 17/05/2021 | WON 5.5-2.5 | Nigel Cook |
| Piltdown (H) | 8.30 | WEDNESDAY | 19/05/2021 | LOST 3.5-4.5 | Dave Barber |
| Pyecombe (H) | 8.30 | WEDNESDAY | 26/05/2021 | WON 7-1 | Mike Grindell |
| Mannings Heath (H) | 8.30 | WEDNESDAY | 02/06/2021 | WON 6-2 | Eryl Williams |
| Pyecombe (A) | 8.30 | MONDAY | 07/06/2021 | LOST 3-5 | Mike Grindell |
| Littlehampton (A) | 8.30 | MONDAY | 14/06/2021 | CANCELLED | Gerry Greensmith |
| Cowdray Park (A) | 8.30 | MONDAY | 21/06/2021 | LOST 2.5-5.5 | Nick Goslett |
| Royal Eastbourne (A) | 8.30 | THURSDAY | 24/06/2021 | LOST 5.5 – 1.5 | Derek Chivers |
| Haywards Heath (A) | 8.30 | MONDAY | 28/06/2021 | LOST 5 – 3 | Ray Dennett |
| Crowborough (H) | 8.30 | WEDNESDAY | 30/06/2021 | WON 6.5-1.5 | Dave Barber |
| Ham Manor (H) | 8.30 | FRIDAY | 03/09/2021 | WON 5 – 1 | Barry Green |
| Piltdown (A) | 8.30 | WEDNESDAY | 07/07/2021 | WON 2.5 – 3.5 | Dave Barber |
| Royal Eastbourne (H) | 8.30 | THURSDAY | 15/07/2021 | WON 7 – 1 | Derek Chivers |
| East Sussex National (H) | 8.30 | WEDNESDAY | 21/07/2021 | CANCELLED | Graham Davey |
| Worthing (H) | 8.30 | FRIDAY | 23/07/2021 | WON 5.5 – 3.5 | Gerry Greensmith |
| Hill Barn (H) | 8.30 | FRIDAY | 30/07/2021 | HONORABLE DRAW | David Bunting |
| Chartham Park(H) | 8.30 | MONDAY | 26/07/2021 | Won 6.5 to 1.5 | Graham Davey |
| Worthing (A) | 8.30 | FRIDAY | 06/08/2021 | LOST 6 – 2 | Gerry Greensmith |
| Seaford Blatchington (A) | 8.30 | MONDAY | 09/08/2021 | Loss 1 to 5 | Bernard Yates |
| Cowdray Park (H) | 8.30 | MONDAY | 16/08/2021 | Win 7 to 1 | Nick Goslett |
| Ham Manor (A) | 8.30 | WEDNESDAY | 18/08/2021 | LOST 5.5 – 1.5 | Barry Green |
| Goodwood (H) | 8.30 | THURSDAY | 02/09/2021 | WON 6.5 – 1.5 | David Bunting |
| Cooden Beach (A) | 8.30 | MONDAY | 13/09/2021 | DRAW | Dave Boys |
| Crowborough (A) | 9.00 | TUESDAY | 21/09/2021 | LOSS | Dave Barber |
| Seaford Blatchington (H) | 8.30 | MONDAY | 27/09/2021 | Abandonned | Bernard Yates |
| Chartham Park (A) | 8.30 | THURSDAY | 28/10/2021 | See new date | Graham Davey |
| Mannings Heath (A) | 8.30 | MONDAY | 04/10/2021 | LOSS 6 – 2 | Eryl Williams |